Abstract
tissues was significantly higher than that in the adjacent normal tissue (73.3% vs 13.3%, P 0.05). 5. Multivariate analysis confirmed that the dual-high expression of SUMO-1 and P53 was an independent factor for predictors of progression risk. Conclusion: There was a high SUMO1 expression in colon cancer tissues. High expression of P53 in colon cancer may be related to SUMO Modification. SUMO1 may be useful as a novel target for therapy in colon cancer as well as a clinical indicator for tumor progression risk.
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