Abstract

the symptom criteria specified (OR: 3.0; 95% CI: 1.1-8.1), although most subjects with esophagitis (90.9%) did not meet symptom criteria for GERD. Subjects with esophagitis experiencedmore severe andmore frequent epigastric burning than subjects without esophagitis (p = 0.050), but no difference was seen for epigastric pain or typical GERD symptoms. Hiatus hernia was associated with the presence of GERD based on symptoms (OR: 25.1; 95% CI: 1.5-426.2) and with esophagitis (OR: 17.8; 95% CI 2.8-113.02). The prevalence of H. pylori infection was 70.8%. No significant associations with H. pylori infection for either esophagitis or symptom-based GERD were found. Conclusions. The spectrum of symptoms and esophageal complications associated with GERD in Shanghai differs from that in Western countries. This has implications for future studies of the epidemiology of GERD in Asia.

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