Abstract

Non-invasive brain stimulation (NIBS) can induce neural plasticity and modify functional recovery among patients with central nervous system (CNS) lesion. The improvement of motor function is task specific. Task specific training is gold standard of rehabilitation training. NIBS is, therefore, often used as pre-conditioning tool for rehabilitation training. Functional motor recovery may based on the increased motor cortex excitability and unmasking of pre-existed pathways with disinhibition of inhibitory interneuron. Reduced interhemispheric inhibition from unaffected hemisphere to affected hemisphere may be one of the mechanism in some limited patients. We review the effect of NIBS in rehabilitation for patients with CNS lesion and show our experience of applying transcranial direct current stimulation (tDCS) combined with electrical stimulation and rTMS, in especially, quadri pulse stimulation. It was supposed that NIBS is effective tool for rehabilitation. It is important to apply NIBS with task specific-rehabilitation training to improve motor function.

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