S1443: Does Guidewire Use Prevent Post-ERCP Pancreatitis? A Meta-Analysis of Randomized Controlled Trials

Abstract

Deep biliary cannulation is important for performing therapeutic endoscopic biliary interventions with varying success rates (50-90%), depending upon experience. Cannulation technique is pivotal in pathogenesis of post-ERCP pancreatitis (PEP). Multiple methods, including the use of guidewire, precut technique, and medications, are used to improve cannulation. To date, the results for guidewire use for prevention of PEP and improving the rate of successful cannulation are conflicting. Therefore, we conducted meta-analysis to assess the role of guidewire use for prevention of PEP and improving cannulation rates.