S141 BMP9 is required for LPS-mediated neutrophil recruitment to PAH-patient derived blood outgrowth endothelial cells with BMPR-II mutations

Abstract

IntroductionHeterozygous mutations in the gene encoding bone morphogenetic protein (BMP) receptor II (BMPR-II) are present in >70% of patients with heritable pulmonary arterial hypertension (hPAH) and 15–26% of idiopathic PAH...