Abstract
S-1 is a kind of fouth-generation oral fluoropyrimidine,including tegafur(FT),5-chloro-2,4-dihydroxypyridine(CDHP),and potassium oxonate(Oxo).S-1 is now used in 80% advanced gastric cancer patients in Japan,it's reported that CR+RR is over 44.6%.Neoadjuvant chemotherapy can reduce tumor loading,degrade the staging,afford operation possibility.S-1 combined with CDDP as a new neoadjuvant chemotherapy,is the most efficient therapy in advanced gastric cancer at present,it's CR can be over 76%. Key words: Chemotherapy,adjuvant; Stomach neoplasms; Cisplatin; S-1
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