Abstract

Signal detection is a promising technique used for prompt detection of novel reactions. It is a modern method of detecting new reaction of a drug. Ubrogepant and Rimegepant are calcitonin gene-related peptide (CGRP) receptor antagonists were approved by US Food and Drug Administration (USFDA) in December 2019 and February 2020 respectively for acute treatment of Migraine. This study was to identify the signal strength for Ubrogepant and Rimegepant associated ADRs using data mining technique in USFDA adverse event reporting system (AERS) database.

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