Abstract
Rutin has been shown be a potent antioxidant that restores impaired vascular reactivity and baroreflex sensitivity in hypertensive rats, mainly by decreasing oxidative stress.
Highlights
Rutin has been shown be a potent antioxidant that restores impaired vascular reactivity and baroreflex sensitivity in hypertensive rats, mainly by decreasing oxidative stress
This study aimed to evaluate the effect of rutin administration on the baroreflex and oxidative stress in serum of rats with renovascular hypertension (2K1C hypertension model) and their normotensive controls
Chronic administration of rutin reduced serum levels of lipid peroxidation in hypertensive rats when compared to 2K1C + saline group (2.24 ± 5.29 vs. 0.93 ± 0.55 nmol de MDA/ml, respectively, p < 0.05)
Summary
Rutin has been shown be a potent antioxidant that restores impaired vascular reactivity and baroreflex sensitivity in hypertensive rats, mainly by decreasing oxidative stress. Rutin reduces oxidative stress in animals with renovascular hypertension Rayssa Duarte*, Alynne Carvalho, Danilo Gadelha, Valdir Braga From 5th Congress of the Brazilian Biotechnology Society (SBBIOTEC) Florianópolis, Brazil.
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