Abstract
In the present investigation, we report the preparation and evaluation of antimicrobial potential of rutin-loaded chitosan nanoparticles (CRNPs). Developed CRNPs were characterized for particle size and zeta potential. Antibacterial potential of CRNPs was evaluated against dental caries pathogen, in vitro. Results revealed that chitosan enhances the anticariogenic potential of rutin. A stability study of pure rutin and CRNPs was performed in simulated saliva fluid. Results revealed that the antibacterial potential of rutin was significantly enhanced by developing it as CRNPs. The MIC and MBC against Bacillus pumilus and Enterococcus faecalis for CRNPs differed significantly compared with bare rutin or chitosan.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
