Abstract
Under these circum-stances, the present work was disclosed during the course ofthe extension of this protocol to the reaction of 2-amino-benzyl alcohol with aldehydes. Herein, we describe aruthenium-catalyzed oxidative coupling and cyclization be-tween 2-aminobenzyl alcohol and aldehydes leading to 3-substituted quinolines.Initial attempts for the oxidative cyclization of 2-amino-benzyl alcohol ( 1 ) with octyl aldehyde ( 2a ) were examinedunder several conditions. Treatment of 1.5 equivalent of 1with 2a in dioxane in the presence of a catalytic amount ofRuCl
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