Abstract
Asthma is a chronic inflammatory airway disease with bronchial hyperresponsivenes causing recurrent episodes of wheezing, dyspnea, chest tightness and cough which typically occur at nighttime or early in the morning. These episodes are due to generalized airway obstruction which is commonly reversible spontaneously or with treatment. Asthma is mainly diagnosed clinically and should be based on the patient's symptoms and signs, lung function testing with investigations of bronchial obstruction reversibility, allergy testing and after exclusion of other diseases. The aim of asthma therapy is achievement and maintenance of asthma control that is maximal resolution of clinical symptoms of the disease.
Highlights
Asthma is a chronic inflammatory airway disease with bronchial hyperresponsivenes causing recurrent episodes of wheezing, dyspnea, chest tightness and cough which typically occur at nighttime or early in the morning
Суточная вариабельность пиковой скорости выдоха (ПСВ) определяется как амплитуда ПСВ между максимальным и минимальным значениями в течение дня
Максимальная доза ингаляционных глюкокортикостероидов (иГКС) до 1 000 мкг в эквиваленте беклометазона дипропионата (БДП) Минимально возможная доза пероральных стероидов Анти-lgE-терапия Пациенты, получающие пероральные стероиды, которые ранее не получали ингаляционной терапии Взрослые и подростки (А); дети в возрасте [5–12] лет (D) – у взрослых рекомендуется метод элиминации или уменьшения дозы стероидных таблеток на иГКС в дозах до 2000 мкг в сутки, если потребуется
Summary
А.Г.Чучалин, З.Р.Айсанов, А.С.Белевский, А.Ю.Бушманов, О.С.Васильева, И.К.Волков, Н.А.Геппе, Н.П.Княжеская, Н.Н.Мазитова, Н.Н.Мещерякова, Н.М.Ненашева, В.А.Ревякина, И.В.Шубин. A.G.Chuchalin, Z.R.Aysanov, A.S.Belevskiy, A.Yu.Bushmanov, O.S.Vasil'eva, I.K.Volkov, N.A.Geppe, N.P.Knyazheskaya, N.N.Mazitova, N.N.Meshcheryakova, N.M.Nenasheva, V.A.Revyakina, I.V.Shubin
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