Abstract
We have studied 3 newborns affected by severe hypoxic encefalopathy in order to determine the brain death by Magnetic Resonance imaging (MRI) (SE T1 weighted axial and sagittal, FSE T2 weighted axial and coronal, FLAIR axial), 1H-Magnetic Spectroscopy (1H-MRS) (single voxel 8 cm3 located in the basal ganglia and in the white matter with PRESS — point resolved spectroscopy- TE 40, 135, 270), diffusion imaging (Dwi) (b value 800–1200) and MR angiography (ToF 2D arterial and ToF 2D venous). In the cases studied in order to permitt a possible organ-transplantation, we have observed the following data: very severe brain oedema with white matter signal hypointensity in T1wi and signal hyperintensity in T2wi, loss of subarachnoid spaces, signal alterations of brainstem and basal ganglia, absent intracranial arterial and venous vascular flow, reduction of NAA/Cr and increase of Lac/Cr in the spectroscopy evaluation, a massive drop in ADC values with different regional distribution. The MRI, MR-angiography, Dwi and 1H-MRS can help in the determination of brain death.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
