Abstract

Chemical analysis of a terrestrial actinomycete (Lv-6-8) isolated from the root zone of Yucca aloiofolia yielded a new anthraquinone possessing a 3-furanone ring system, rubimycinone A (1). The structure of 1 was elucidated based on spectroscopic methods including UV, HR-ESIMS and 1D, and 2D NMR data. Rubimycinone A (1) displayed modest to good antibacterial and cytotoxic activity against a panel of Gram positive strains and various cancer cell lines.

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