Abstract
The reaction of N-aryl acrylamides with maleimides in the presence of a ruthenium/rhodium catalyst and Cu(OAc)2·H2O provided succinimide-substituted oxindole derivatives in good to excellent yields. In the reaction, 3,3'-disubstituted oxindoles are produced via a C-H alkylation and intramolecular oxidative cyclization sequence. The proposed mechanism was supported by competition experiments, deuterium labeling studies, and radical scavenger experiments.
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