Abstract

SummaryRtpca is an R package implementing methods for inferring protein–protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages.Availability and implementationRtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca).Supplementary information Supplementary data are available at Bioinformatics online.

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