Abstract
Objectives Our objective was to report perinatal outcome during the first three years of an emerging centre for laser photocoagulation in twin-twin transfusion syndrome (TTTS) and to compare with outcome observed earlier in the same centre when management consisted in recurrent amniodrainage. Patients and methods We conducted a single centre retrospective study. We compared perinatal outcome of 19 consecutive cases of mid trimester TTTS managed by amniodrainage over a 10-year period with 49 cases of TTTS managed by laser photocoagulation over a 3-year period. Results Laser photocoagulation increased survival rate at birth ( P = 0.02) and at postnatal day 28 ( P = 0.01). Neurologic and cardiologic complications did not differ significantly ( P = 0.5 and P = 0.3 respectively). We observed a significant increase in survival of the donor after laser coagulation at birth ( P = 0.04). Discussion and conclusion Our study demonstrated better outcome after laser photocoagulation. Early results of an emerging centre appeared comparable to those of more experienced centres.
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