Abstract
Mature T-cell and NK-cell neoplasms comprise a heterogenous group of diseases of lymphoid origin. Approximately 10–15% of the diagnosed lymphomas make up to this category. These neoplasms are characterized by differentiated clinical and pathomorphological traits, frequent extranodal mani¬festations and poor outcome. Given their relatively rare occurrence, high heterogeneity and lack of randomized clinical trials, work out of unified recommendations is difficult. Nevertheless, chemo¬therapy and hematopoietic stem cell transplantation seem to be effective in up-front and relapsed and refractory setting. In this publication we discuss the guidelines of diagnosis and treatment of this heterogenous malignancy group.
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