Abstract
Women’s life stages are based on their reproductive cycle. This cycle begins with menstruation and ends with menopause. Aging is a natural phenomenon that affects all humans, and it is associated with a decrease in the overall function of the organism. In women, aging is related with and starts with menopause. Also, during menopause and postmenopausal period, the risk of various age-related diseases and complaints is higher. For this reason, researchers were pushed to find effective remedies that could promote healthy aging and extended lifespan. Apitherapy is a type of alternative medicine that uses natural products from honeybees, such as honey, propolis, royal jelly, etc. Royal jelly is a natural yellowish-white substance, secreted by both hypopharyngeal and mandibular glands of nurse bees, usually used to feed the queen bees and young worker larvae. Over the centuries, this natural product was considered a gold mine for traditional and natural medicine, due to its miraculous effects. Royal jelly has been used for a long time in commercial medical products. It has been demonstrated to possess a wide range of functional properties, such as: antibacterial, anti-inflammatory, vasodilatative, hypotensive, anticancer, estrogen-like, antihypercholesterolemic, and antioxidant activities. This product is usually used to supplement various diseases such as cardiovascular disease, Alzheimer’s disease, sexual dysfunctions, diabetes or cancer. The main objective of this study is to highlight the effectiveness of royal jelly supplementation in relieving menopause symptoms and aging-related diseases. We also aimed to review the most recent research advances regarding the composition of royal jelly for a better understanding of the effects on human health promotion.
Highlights
Menopause represents a transitional phase into a woman’s life, during which a wide range of changes in metabolism, physiology, mental, and physical well-being occur [1]
Despite there is a small number of studies in this field, the results indicated that anti-aging activity of royal jelly and its compounds on human cell lines, supports previous results reported for model organisms
Role in modulating the natural mechanisms of natural aging. This product has demonstrated its efficiency the alleviation of postmenopausal complaints. It could be successfully used by Accumulating evidence from the most recent studies indicated that royal jelly possesses a significant postmenopausal women as a dietary supplement foraging
Summary
Menopause represents a transitional phase into a woman’s life, during which a wide range of changes in metabolism, physiology, mental, and physical well-being occur [1]. Menopausal symptoms usually have a significant negative impact on the overall quality of life and become a psychosocial impairment. The majority of these symptoms are a consequence of estrogen withdrawal or a prolonged estrogen deficiency [2]. Molecules 2020, 25, 3291 night sweats) osteoporosis and vaginal atrophy [3]. These problems are treated with hormonal replacement therapy but the risk of undesirable adverse effects such as breast cancer, abnormal uterine bleeding or breast tenderness sometimes outweighs the benefits, which is why more natural alternatives tend to be used [4,5]. Soybeans and red clover are the most well-known natural alternatives to conventional hormone replacement therapy, but their efficiency is still highly debated [6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
