Abstract
The whole blood clotting time (WBCT) determined in silicone‐treated tubes was compared with the recalcification time of citrated plasma in silicone tubes (RTST), the partial thromboplastin time (PTT), and the activated partial thromboplastin time (APTT) in a group of dicumarol‐treated patients.By linear regression analyses, correlation coefficients of about 0.7 were found when WBCT was compared with RTST and APTT. In a group of 9 patients with only moderately decreased factor II, VII, X activity, the clotting times of the investigated methods exceeded the upper normal limits. In seven of these patients two or more of the tests coincided. Although there were considerable disaggrements among the tests, it is probable that they at least partly measure the same qualities.A quality control study over more than one year showed that the PTT test varied considerably but that the APTT test carried out with the commercial reagent Platelin plus Activator varied remarkably little. To test the total clotting potential of plasma in routine laboratory work, APTT seems to be the test of choice.
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