Routine office Hysteroscopy with Endometrial Biopsy in an Infertility Clinic

Abstract

Study Objective: To evaluate the role of diagnostic hysteroscopy with endometrial biopsy in infertile patient work up.Design: Retrospective study.Setting: Infertility and gynecologic endoscopy private clinic.Patients: The mean age was 35,64 (25 – 47 year). Fifty-four patients underwent to diagnostic office hysteroscopy from august 2004 to September 2008.Intervention: All patients were infertile and haven't had this hysteroscopy before. First author performed the exams in proliferative phase. Aspirative endometrial biopsy usually was done immediately after the hysteroscopy.Measurements and Main Results: Alterations that could cause infertility or IVF implantation fail were found in 22 out of 54 (40.7%) patients. Endometrial polyps 50% (11/22); endocervical polyps 31.8% (7/22); endometrits 27.3% (6/22); cervical canal estenosis 9,1 (2/22), complex hyperplasia without atipia 4.5% (1/22).Conclusion: Routine diagnostic Office hysteroscopy with biopsy could diagnose uterine alterations in 22 infertile patients (40.7%) that could be the cause of infertility or implantation fail. Study Objective: To evaluate the role of diagnostic hysteroscopy with endometrial biopsy in infertile patient work up. Design: Retrospective study. Setting: Infertility and gynecologic endoscopy private clinic. Patients: The mean age was 35,64 (25 – 47 year). Fifty-four patients underwent to diagnostic office hysteroscopy from august 2004 to September 2008. Intervention: All patients were infertile and haven't had this hysteroscopy before. First author performed the exams in proliferative phase. Aspirative endometrial biopsy usually was done immediately after the hysteroscopy. Measurements and Main Results: Alterations that could cause infertility or IVF implantation fail were found in 22 out of 54 (40.7%) patients. Endometrial polyps 50% (11/22); endocervical polyps 31.8% (7/22); endometrits 27.3% (6/22); cervical canal estenosis 9,1 (2/22), complex hyperplasia without atipia 4.5% (1/22). Conclusion: Routine diagnostic Office hysteroscopy with biopsy could diagnose uterine alterations in 22 infertile patients (40.7%) that could be the cause of infertility or implantation fail.