Abstract
Genetically modified foods have become pervasive in diets of people living in the US. By far the most common genetically modified foods either tolerate herbicide application (HT) or produce endogenous insecticide (Bt). To determine whether these toxicological effects result from genetic modification per se, or from the increase in herbicide or insecticide residues present on the food, we exposed fruit flies, Drosophila melanogaster, to food containing HT corn that had been sprayed with the glyphosate-based herbicide Roundup®, HT corn that had not been sprayed with Roundup®, or Roundup® in a variety of known glyphosate concentrations and formulations. While neither lifespan nor reproductive behaviors were affected by HT corn, addition of Roundup® increased mortality with an LC50 of 7.1 g/L for males and 11.4 g/L for females after 2 days of exposure. Given the many genetic tools available, Drosophila are an excellent model system for future studies about genetic and biochemical mechanisms of glyphosate toxicity.
Highlights
The use of genetically modified crops (GMOs) has increased dramatically in industrial agriculture since marketing began in 1996, first in herbicide tolerant (HT) soybeans and insect tolerant (Bt) corn, potato, and cotton
Lifespan was not affected by the type of corn in the diet overall
While it appears that for males, the organic treatment had longer lifespan than the other treatments, this difference was not significant as part of a whole model analysis
Summary
The use of genetically modified crops (GMOs) has increased dramatically in industrial agriculture since marketing began in 1996, first in herbicide tolerant (HT) soybeans and insect tolerant (Bt) corn, potato, and cotton. 100% of sugar beets [2] planted for commercial production in the US in 2016 or 2017 Worldwide, they accounted for 78% of soybeans, 33% of corn, and 24% of canola in 2016 [3]. In both two strains differed slightly in their response to duration of exposure (exposure: F = 3.01, p = 0.0871; strains, the response was non-significant after two days of exposure, with nearly as many exposed exposure × strain: F = 7.18, p = 0.0091; exposure × concentration: F = 35.7, p < 0.0001) In both strains, flies surviving all treatments as those exposed to control medium. After seven days both the response was non-significant after two days of exposure, with nearly as many exposed flies
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
