Abstract

We detected rotavirus G5P[6] with a long RNA pattern in a Vietnamese child with diarrhea. Viral outer capsid protein VP7 and VP4 genes suggest that it likely originated from porcine rotavirus either by genetic reassortment or as whole virions. To our knowledge, this is the first report of human rotavirus G5 in Asia.

Highlights

  • We detected rotavirus G5P[6] with a long RNA pattern in a Vietnamese child with diarrhea

  • Many people in Vietnam live in close contact with domestic animals, which may promote interspecies transmission of rotaviruses and reassortment of human and animal rotaviruses

  • We hypothesized that in rural Vietnam, some rotavirus infections are caused by animal rotaviruses or animal–human reassortants

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Summary

Issue Date

This document is downloaded at: 2020-10-05T16:14:39Z http://naosite.lb.nagasaki-u.ac.jp. Viral outer capsid protein VP7 and VP4 genes suggest that it likely originated from porcine rotavirus either by genetic reassortment or as whole virions. To our knowledge, this is the first report of human rotavirus G5 in Asia. Rotavirus accounts for 55% of diarrheal diseases in Vietnam, prevalent serotypes are G1, G2, G3, G4, and G9, and 3% of rotaviruses were untypeable (3). This low percentage of untypeable strains was unanticipated because it is assumed that developing countries are the source of unusual rotavirus strains (4). We hypothesized that in rural Vietnam, some rotavirus infections are caused by animal rotaviruses or animal–human reassortants

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This study was supported by the grant The Collaborative
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