Abstract
BackgroundChanges in coagulability during the hyperacute phase within 24 h after transcatheter aortic valve implantation (TAVI) for Heyde’s syndrome, or aortic stenosis complicated by gastrointestinal angiodysplasia and acquired coagulation dysfunction, have not been clarified. We evaluated perioperative changes in coagulability using rotational thromboelastometry (ROTEM).Case presentationA female patient with Heyde’s syndrome in her 80s underwent TAVI. ROTEM showed coagulation dysfunction before and at 6 h after surgery. Improvements in coagulation function started at 12 h after surgery. Based on ROTEM findings, oral administration of antiplatelet agents was started on the day after surgery. No hemorrhagic complications were observed in the postoperative phase.ConclusionsEvaluation of coagulation function using ROTEM was useful for monitoring perioperative hemostasis and coagulation in this patient.
Highlights
Changes in coagulability during the hyperacute phase within 24 h after transcatheter aortic valve implantation (TAVI) for Heyde’s syndrome, or aortic stenosis complicated by gastrointestinal angiodysplasia and acquired coagulation dysfunction, have not been clarified
In the FIBTEM assay, abnormalities in platelet function and decreased capability for fibrin polymerization caused by impairment of coagulation factors can be differentiated by evaluating the capability for fibrin polymerization when platelet aggregation is inhibited by a platelet aggregation inhibitor and the extrinsic coagulation pathway is stimulated by tissue factor [6,7,8]
Compared with plasma-based tests, we believe that rotational thromboelastometry (ROTEM), which monitors the coagulation system using whole blood, can comprehensively and promptly evaluate coagulation dysfunction not reflected by Prothrombin time (PT) or activated partial thromboplastin time (APTT)
Summary
Changes in coagulability during the hyperacute phase within 24 h after transcatheter aortic valve implantation (TAVI) for Heyde’s syndrome, or aortic stenosis complicated by gastrointestinal angiodysplasia and acquired coagulation dysfunction, have not been clarified. By measuring PT and APTT, abnormalities in extrinsic and intrinsic coagulation factors are assessed using plasma; neither platelet function, including its interaction with the blood coagulation system, nor the firmness of blood clots can be evaluated [8].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
