Abstract

Rosai-Dorfman disease (RDD) also known as sinus histiocytosis with massive lymphadenopathy is a rare disorder of histiocytes characterized histologically by intracellular engulfment of lymphocytes. It may occur in any age group, but is most commonly seen in children and young adults. It is characterized by painless, bilateral massive cervical lymphadenopathy. In approximately one-third of patients it can occur in a variety of extranodal sites where it can have abundant plasma cells and sclerosis. We present a rare case of RDD in a pregnant women who presented with unilateral cervical lymph node with features of RDD showing increase in plasma cells and sclerosis as seen in extranodal sites.

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