Abstract
Rosai-Dorfman Disease (RDD) also known as Sinus Histiocytosis With Massive Lymphadenopathy (SHML) is a rare and benign non- Langerhans histiocytosis. First described in 1965 by Destombes [1] then in 1969 by Rosai and Dorfman, this disease is characterized by benign histiocytic proliferation with frequent lymphophagocytosis (emperipolesis) [2]. All ages are affected but most of the patients present before age 20, with a slight male predominance [3]. Rosai-Dorfman disease usually presents as bilateral, massive and painless cervical lymphadenopathy [2]. Extra-nodal involvement is found in 30-40% of cases and is more common in the head and neck region [3]. The disease is often benign and self limiting requiring only observation. In some cases, the condition can be severe. Several treatments have been used with varying efficiency [4]. We report a case of RDD in a male Tunisian patient treated and followed up in our department.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
