Rosai Dorfman disease : A rare association of sero positive rheumatoid arthritis

Abstract

Rosai-Dorfman disease (RDD) is a rare self-limiting histiocytic proliferative disorder that mostly presents with cervical lymphadenopathy with constitutional symptoms. It is associated with connective tissue disease in 10% of cases. Here we present a case of 14-year-old boy who presented with a prolonged fever, arthralgia and generalize lymphadenopathy. Eventually the diagnosis of RDD associated with early Rheumatoid arthritis was made.