Rosacea Keratitis with Corneal Perforation: 2-Case Report

Abstract

Purpose: To report two cases of ocular rosacea with corneal perforation Method: Interventional case report Result: Two young females presented with a history of recurrent red eye and photophobia in both eyes for years, and had received intermittent topical medication elsewhere. They both had gradually decreased vision in one eye. They also had chronic blepharoconjunctivitis and corneal opacities with neovascularization formation. Corneal melting and perforation occurred in one eye later. One of them had facial erythema and telangiectasia. We performed lamellar keratoplasty combined with topical 0.1% betamethasone and 0.3% ciprofloxacin 4 times daily. 250 mg of oral tetracycline 4 times daily or 100mg of doxycycline twice a day were also added. After the treatment, the ocular surface became silent and the corneal neovascularization decreased. Conclusion: Ocular rosacea may cause severe complications such as melting, and even perforation. Lamellar keratoplasty can preserve vision in cases of corneal perforation. The combined usage of topical steroid and systemic tetracycline or doxycycline can decrease ocular inflammation and recurrence.