Year-end Sale % OFF 
Abstract
Histamine plays an important role in broncho constriction mediated by histamine receptors which provoke bronchial asthma attack. In this study, we measured H 1 and H 2 receptors in the guinea pig lung membrane fraction and obtained the following results. The maximum binding ( B max) of H 1 receptors in the guinea pig lung membrane fraction was significantly higher in the OA-sensitized group than that in the non-sensitized group, but affinity ( K d) did not differ between the groups. Otherwise, the maximum binding ( B max) of H 2 receptors in the guinea pig lung membrane fraction was significantly lower in the OA-sensitized group than that in the non-sensitized group. But affinity ( K d) did not differ between the groups. These findings suggest a close association of Histamine receptors both H 1 and H 2 in the pathology of asthma.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
