Abstract
Intracranial aneurysm is a complicated disease caused by multifactors. Its mechanisms of the formation and rupture remain unclear. Cytokines are the general designation of the protein with bioactive small molecules secreted by the activated cells. They transmit information between the cells and regulate the physiological and pathological processes of cells. Several cytokines are involved in intracranial aneurysm formation and rupture. This article emphatically elaborates the roles of cytokines in the formation of intracranial aneurysms. Key words: Intracranial aneurysm; Cytokines; Inflammation; Tumor necrosis factor-α; Interleukins; Transforming growth factor-β; Platelet-derived growth factor
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