Abstract
The intracellular signal transduction pathways play an important role in the occurrence and development of thyroid cancer. Mitogen activated protein kinase (MAPK) signal transduction pathway, phosphatidylinositol 3-kinase (PI3K)-AKT pathway, NF-κB pathway and RASSF1-MST1-FOXO3 pathway affect the occurrence and development of thyroid cancer by modulating the activity and expression of specifical proteins, and determine the growth and apoptosis of thyroid cancer cells. Key words: Thyroid neoplasms; Signal transduction pathways
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