Roles and controls of mTOR in the heart.Focus on “mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy”

Abstract

in their article in this issue, Song et al. ([24][1]) present evidence that mammalian target of rapamycin (mTOR), a serine-threonine kinase, is an endogenous suppressor of the inflammatory response that complicates myocardial hypertrophy induced by aortic constriction. This inflammatory process has