Abstract

Floating drug delivery system is the form of gastro - retentive drug delive ry system. That controls kinetic release rate of drug to a specific site for its pharmacological action. These are achieved by use of various polymeric substances including natural polymer such as xanthan g um. This delivery system prolongs the retention ti me of the drug in the stomach as compared to conventional dosage form. The present article highlights the use of xanthan gum for the formulation of the gastro - retentive drug delivery system especially with natural polymer (xanthan gum). The main goal of an y drug delivery system is to achieve desired concentration of the drug in blood or tissue, which is therapeutically effective and non toxic for a prolonge d period . Oral delivery of drugs is by far the most preferable route of drug delivery due to the ease of administration, patient compliance and flexibility in formulat ion etc. From immediate release to cite specific delivery, oral dosage forms have really progressed.

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