Abstract
Very early-onset inflammatory bowel disease (VEO-IBD) is defined as IBD onset before 6 years of age and some cases arecaused by unique monogenic disorders that require specific treatments such as stem cell transplantation. We identified threechildren with VEO-IBD of whom two had monogenic disorders. In cases 1 and 2, ultrasound revealed isolated colonic distributionand the loss of wall stratification. In case 3, mesentery inflammation was evident. Bowel ultrasound showed variablefindings due to differences in the inflammation distribution within the bowel. In order to diagnose VEO-IBD, sonographersshould carefully evaluate the intestinal wall thickness and stratification and the distribution of inflammation in the intestine andmesentery. These findings may aid the diagnosis of VEO-IBD.
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