Abstract
Tahira Shahzadi* Author Affiliations Department of Obstetrics and Gynecology, Dr. Sulaiman Al Habib Hospital, Saudi Arabia Received: April 14, 2020 | Published: May 08, 2020 Corresponding author: Tahira Shahzadi, Department of Obstetrics and Gynecology, Dr. Sulaiman Al Habib Hospital, Khurais Road, Ar Rayan, Riyadh, Saudi Arabia DOI: 10.26717/BJSTR.2020.27.004520
Highlights
Leiomyoma Uteri or Fibroid uterus is common benign tumours
SPRMs are synthetic compounds that act at Progesterone receptor sites showing either agonistic or antagonistic activity depending upon changes in progesterone receptors [1,2]
SPRMs can cause changes in endometrium known as progesterone receptor modulator associated endometrial changes (PAECs)
Summary
Leiomyoma Uteri or Fibroid uterus is common benign tumours. They can present as asymptomatic in 2/3rd of cases and with symptoms in 1/3rd of cases. Mode of treatment depends upon many factors e.g., age, fertility wishes, symptoms, size and location. Role of SPRMs to Reduce Size of Fibroid Preoperatively and Long Term Medical Management
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