Abstract

Introduction: Current echocardiographic parameters have a limitation in assessing mitral valve (MV)apparatus in rheumatic mitral stenosis (MS) patient. In the current study, we use 2 dimensional (2D)longitudinal strain (S) and strain rate (Sr) imaging in evaluating the papillary muscle longitudinal strain (LS) as an objective and quantitative echocardiographic parameter with high reproducibility in the assessment of MV apparatus in patients with mild to moderate rheumatic MS with preserved ejection fraction (EF%). Patients and Method: The study included 40 patients with established diagnosis of MS subdivided in to 31 patients with moderate MS (mean age: 32 ± 5) and 9 patients with mild MS (mean age: 31 ± 6). 20 healthy individuals (mean age 31 ± 6) as a control for cases. The mitral valve area (MVA) was estimated using planimetry and pressure half time (PHT) methods. 2D longitudinal systolic S and Sr imaging was carried out for all participants from the apical long axis (LAX), 4 chamber (4C), 2 chamber (2C) views. Global longitudinal systolic S and Sr were estimated by averaging the 3 apical views. Longitudinal myocardial strain of papillary muscle PMs was assessed by the use of the free strain method from apical 4 chamber view for the antrolateral papillary muscle (APM) and apical long axis view for postromedial papillary muscle (PPM). Results: Patients with MS had significantly decreased longitudinal LV systolic S and Sr in comparison with control group (p Conclusion: Patients with MS and preserved EF% had decreased APM-LS & PPM-LS in comparison with control group, and had decreased longitudinal LV systolic S and Sr when compared with control group. 2D strain as well as Sr imaging might be a useful method for assessment of mitral valve apparatus in patients with MS & preserved EF%.

Highlights

  • Current echocardiographic parameters have a limitation in assessing mitral valve (MV) apparatus in rheumatic mitral stenosis (MS) patient

  • Patients with MS and preserved EF% had decreased anterolateral papillary muscle longitudinal strain (APM-longitudinal strain (LS)) & posteromedial papillary muscle longitudinal strain (PPM-LS) in comparison with control group, and had decreased longitudinal left ventricle (LV) systolic S and strain rate (Sr) when compared with control group. 2 dimensional (2D) strain as well as Sr imaging might be a useful method for assessment of mitral valve apparatus in patients with MS & preserved EF%

  • No significant difference was observed in interventricular septum (IVS) and PW thickness, LVESD, LVEDD, EF% and FS% in patients with MS when compared with the control group (p > 0.05), LA diameter was significantly higher in patients with MS in comparison with the control group (

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Summary

Introduction

Current echocardiographic parameters have a limitation in assessing mitral valve (MV) apparatus in rheumatic mitral stenosis (MS) patient. We use 2 dimensional (2D) longitudinal strain (S) and strain rate (Sr) imaging in evaluating the papillary muscle longitudinal strain (LS) as an objective and quantitative echocardiographic parameter with high reproducibility in the assessment of MV apparatus in patients with mild to moderate rheumatic MS with preserved ejection fraction (EF%). Chronic affection of the MV leaflets in rheumatic patients in particular with recurrent episodes includes chronic scarring [3] These valvular changes become progressive over time resulting in funnelshaped stenotic MV. In MS, if it is considered that fibrosis mainly involves the valve along with nearby structures such as the papillary muscles APM & PPM, the measurement of longitudinal strain of papillary muscles in addition to the underlying myocardium by 2D strain and Sr is new quantitative method for assessment of MV apparatus

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