ROLE OF TRIPLE PHASE CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN HEPATIC LESIONS AND THEIR CYTOPATHOLOGICAL CORRELATION

Abstract

AIMS: To evaluate the enhancement patterns of hepatic lesions on triple phase contrast enhanced computed tomography and to correlate the CT ndings of hepatic lesions with cytological ndings on ne needle aspiration cytology (FNAC). Settings and Design: This prospective observational study was carried out at Department of Radiodiagnosis, Gobind Singh Medical College and Hospital, Faridkot. The study was approved by the Institutional Ethics Committee. Source of Data: A total of 75 patients who had hepatic lesions on ultrasonography and clinical suspicion of focal hepatic lesions were referred for CECT abdomen. Findings of Triple phase CT for hepatic lesions were correlated with cytopathological ndings. Methods and Material: A Triphasic CECT abdomen was performed on Siemens Somatom Perspective 128 slice scanner in the Department of Radiodiagnosis, Guru Gobind Singh Medical College and Hospital, Faridkot. The entire liver was scanned successively, in arterial, portovenous and delayed phases. A 5mm collimation and 5mm/sec table speed were used. After obtaining a digital scout view, unenhanced scan of the liver was obtained.1.5ml/kg body weight of 300mgI/ml iodinated contrast material was administered by using a pressure injector at a rate of 3.0 mL/s using a pressure injector.USG/CT guided FNAC was done. CT imaging ndings were classied as benign or malignant by correlating them with cytopathological ndings. Results: The present study inferred that Triple phase CECT is a highly sensitive and specic imaging modality for detection and characterization of hepatic lesions with an overall sensitivity and specicity of 100.00 % (95% C.I. 92.45% to 100%) and 92.86% (95% C.I. 76.50% to 99.12%)respectively when correlated with cytopathological ndings. Conclusions: It is inferred from our study that triple phase CECT is highly sensitive and specic imaging modality for detection and characterization of hepatic lesions with wide availability in the present scenario.