Abstract

SummaryA significant decrease in liver nonprotein sulfhydryl levels (LNPSH) was demonstrated in intact, hypophysectomized and adrenalectomized female rats in response to cold and restraint. A similar response was demonstrated following epinephrine injection. Neither ACTH nor cortisol replacement was necessary for this response. It is concluded that maximum LNPSH depletion during cold and restraint can be effected through stimulation of the sympathetic nervous system although other mechanisms are operative in intact animals.

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