Abstract

The sensitivity to X-rays in the albino rat was studied following destruction of the olfactory bulbs. The two procedures of conditioning an aversion to saccharin solution with X-rays as the unconditioned stimulus and conditioned bar press suppression with X-rays as the warning stimulus were both used in testing the sensitivity to the ionizing radiation. The profound aversion to saccharin flavored water, obtained in rats after a single pairing of X-rays with the saccharin solution, was found to be diminished in animals which had olfactory ablations. The conditioning of sham operated animals and those with frontal lesions resulted in the usual significant saccharin aversion. The immediate detection of X-rays was profoundly affected by removal of the olfactory bulbs. Animals which had previously been conditioned to suppress a bar-pressing response in the presence of X-rays failed to show this suppression after complete removal of the olfactory bulbs. When ablation was incomplete, with removal of tissue from the frontal lobes, or with sham operations, the animals continued to show the suppression effect at the onset of X-ray exposure.

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