Abstract

The N-methyl-D-aspartate (NMDA) type of glutamate receptor channel has been shown to be involved in learning and memory, probably through NMDA receptor-dependent long-term potentiation (LTP). NMDA receptor antagonists such as dizocilpine (MK-801) and aminophosphonovaleric acid (APS) affect memory of several tasks and block LTP in several brain areas. Both memory and NMDA receptor-dependent LTP are also blocked by the gamma-aminobutyric acid type A (GABA a) receptor agonist muscimol […] Role of the N-methyl-D-aspartate receptor in the enhancement of inhibitory avoidance [...]

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