Abstract
During the 1950s, there was a need to bring the discoveries of basic science to the bedside by supporting clinical investigation in the universities in a specific and systematic way. Under the leardership of James Shannon at the National Institutes of Health. Senator Lister Hill in the Congress, and influential advocates of clinical research like Elliot V. Newman, the General Clinical Research Center (GCRC) program was established «to provide a carefully controlled research environment, centered around patients, where physicians and scientists can define and attempt to conquer unsolved disease problems affecting humans»
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