Abstract
In predisposed baboons (Papio papio), intermittent light stimulation (ILS) at 25 Hz may induce cortical spikes which symmetrically occupy both fronto-rolandic cortical areas and are accompanied by myoclonic jerks. When ILS is pursued, spikes are transformed into spike-waves or polyspike-waves and can have the capacity to either self-perpetuate after cessation of ILS in an “after-discharge” or followed by a generalized tonicclonic seizure. Electrographically, seizures start in the two frontorolandic areas simultaneously, and quickly diffuse to all brain structures except the rhinencephalon. Monocular as well as binocular ILS induces paroxysmal discharges (PDs) and seizures which, in both cases, occur bilaterally and symmetrically. In naturally photosensitive animals, PDs and seizures induced by ILS never start in the occipital areas.
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