Role of TGF-β1-like factors in the embryonic development of the mollusc Viviparus ater (Gastropoda)

Abstract

Summary The embryonic development of the gastropod Viviparus ater was examined by histochemical procedures as well as by ontogeny of the expression of TGF-β1—and TGF-β type II receptor-like molecules. Developmental stages show specific spatial distributions of molecules immuno-reactive to anti-TGF-β1 and -TGF-β-receptor antibodies. These molecules are present early during development. They were detected at stage (10% of embryonic development) and remained present during further development and in the most advanced stages. These findings support a role for TGF-β1-related factors in pattern formation and the growth of various organs in V. ater.