Abstract
Purpose: To nd the efcacy of topical tetracycline in corneal neovascularization. Material and Methods: In this prospective observational clinical analysis, patients more than fteen year's age of either sex were enrolled. Anterior segment slit lamp examination was performed. Fluorescein 1% dye and rose bengal were used to stain cornea at the bed and margins simultaneously. The area of corneal vascularization was measured in mm using 0.5% uorescein dye. The percentage of neovascularized corneal areas to the entire cornea was calculated. Result: Out of twenty eight patients, twenty one completed follow up period of four months. Among 21 patients, males were 10 (47.6%) and females 11 (52.38%) with unilateral and bilateral corneal neo-vascularization. 15 (71.42%) responded well and showed reduction in corneal new vessels from 7 mm pre-treatment to 2 mm (overall) post treatment at the end of fourth month. Six patient showed poor or no response due to extended brosis. Conclusion: Topical tetracycline has remained quite instrumental in reducing supercial epithelial and sub-epithelial corneal new vessels.
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