Abstract

Blood leukocytes from 30 patients with allergy to tuberculin and bacterial antigens were treated with antithymus (ATS) or anti-immunoglobulin serum (AIGS), after which the leukocyte migration inhibition (LMI) test was carried out with these antigens. ATS abolished LMI by tuberculin and sometimes by bacterial antigens (staphylococcal, streptococcal, etc.). AIGS frequently abolished LMI caused by bacterial antigens but not by tuberculin. In other cases treatment with any serum abolished LMI by antigens or, conversely, it was abolished only by treatment with both antisera in turn. The type of lymphocytes (T or B) determining the reaction to the same antigen in the secondary immune response differed in different patients and also differed in the same patient for different antigens. Five types of interaction between lymphocytes and antigen in the LMI test were distinguished.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.