Abstract
Surface activity of antiarrhythmic drugs and their effect on lipid-containing interphases were studied. Compound No. 7351 (diethylaminopropyl ester of diphenylisopropylacetic acid), Fubromegan, methyldiazine, propranolol, quinidine, novocainamide, xylocaine, and trimecaine were shown to be surface active. The curves of surface activity and, in particular, of interphase activity and those of antiarrhythmic action follow parallel courses. The most active antiarrhythmic compound (No. 7351) increased the electrical conductivity of a lecithin bilayer membrane much more strongly than novocainamide.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
