Role of SNEDDS as Novel Approach for Targeted Drug Delivery: A Review

Abstract

Nanotechnology has become a wide range in pharmaceutical sciences, which has an effect on various drug delivery research from the last 10 years. The developed technology is being explored for the better therapeutic performance of drugs by enhancing the solubility of water-hating drugs (hydrophobic drugs), increasing permeability, regulating drug disposition and biodistribution, and permitting the targeted delivery of drugs. Nanotechnology is broadly categorized into drug nanoparticles or nanosuspension, nanocarriers like lipids, polymeric, and inorganic nanocarriers, as these nanocarriers involve liposomes and microemulsions nanoemulsions, lipid core micelles, solid lipid nanoparticles which are used for the targeted drug delivery systems.2 Based on this technology, the drug components that have poor aqueous solubility, permeability, bioavailability, and instability in physiological medium, the nanoemulsions are selected to enhance the properties. Nanoemulsions are group of heterogeneous with two immiscible liquids as o/w or w/o with droplet size ranges between 20 to 200 nm after the method preparation, before the term nanoemulsions, these are termed as mini-emulsions, micro-emulsions, submicron emulsions, and ultrafine emulsion due to unclear emulsions based on their size of the particles present. Therefore, to overcome the confusion in identifying the actual term, the particles size is within limits or in range, and the main factor is the emulsion, which is indicating transparent, are termed as nanoemulsions and slightly different called microemulsions.