Abstract

<p><strong>Background:</strong> Maternal morbidity related to infection after caesarean section has been reported to be higher than that of vaginal delivery. The prevention of infection in patients undergoing caesarean section is a major challenge, particularly in hospitals, where there is frequent chance of cross infection due to overcrowding. <strong></strong></p><p><strong>Objective:</strong> The present study was undertaken to see the efficacy of single dose cetriaxone as a prophylaxis in elective caesarean section to prevent postop­erative infection. <strong></strong></p><p><strong>Methods:</strong> This cross sectional study was conducted on 100 patients who underwent elective caesarean section where single dose of Ceftriaxone was used as prophylaxis in the Department of Obstetrics & Gynaecology, Bang­abandhu Sheikh Mujib Medical University Hospital, between January to June 2010. The outcomes measures were post­operative febrile morbidity, wound infe-ction and other infections (urinary tract infection, chest infection). Data were analysed using statistical package for social sciences (SPSS) version 11.5.</p><p><strong>Results:</strong> Over one-third (38%) patients age group was between 18 -25 years, 56% in between 25 -35 years and 6% were over 35 years old. Nearly half(46%) was anemic (haemoglobin< 11 g/dl) and 16% was obese (BMI≥28 kg/m<sup>2</sup>). All the patients were operated by obstetricians of same level. Three per cent patients developed wound infection, 5% developed other infections like UTI and chest infection and 7% had febrile illness. Among the several factors suspected to be associated with post operative complications, preoperative anaemia, long duration of operation (>60 minutes) and prolonged hospital stay (>1 week) were found to be significantly assocated with postoperative complications.</p><p><strong>Conclusion:</strong> The present study suggests that single dose prophylactic antibiotic ceftriaxone given 1 hour before operation in patients with cesarean section deliveries reduces the chance of postoperative infection to a bare minimum.</p>

Highlights

  • Caesarean section (CS) delivery is a surgical operation to deliver ababy through an incision in the uterus

  • The present study suggests that single dose prophylactic antibiotic cefhiaxone given I hour before operation in patients with cesarean section deliveries reduces the chance of postoperative infection to a bare minimum

  • Demographic characteristics of the women selected for study showed that 38% study subject were in the age

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Summary

Introduction

Caesarean section (CS) delivery is a surgical operation to deliver ababy through an incision in the uterus. Maternal morbidity related to infection after caesarean section has been reported to be 8-fold higher than after vagtnal delivery. A system aticreview in the Cochrane Library concluded that antibiotic prophylaxis in all cases of cesarean section significantly reduce the incidence of puerperal infections. Matemal morbidity related to infection after caesarean section has been reported to be higher than that of t, I vaginal delivery. The prevention of infection in patients undergoing caesarean section is a major challenge, r in hospitals, where there is frequent chance of cross infection due to overcrowding. Conclusion: The present study suggests that single dose prophylactic antibiotic cefhiaxone given I hour before operation in patients with cesarean section deliveries reduces the chance of postoperative infection to a bare minimum

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