ROLE OF SERUM LDH LEVELS IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY

Abstract

Hodgkin's lymphoma (HL) constitutes around 30% of all lymphomas . IPS is used for the risk stratication of advanced stage HL but it lack applicability to the early stage cases ..In this prospective cohort study, we aim to conrm the relationship between hsCRP levels with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the serum LDH levels and the treatment response showed that the low levels of serum LDH level were associated with more advanced stages.. Univariate analysis showed that there was no signicant correlation of interim treatment response as well as end of treatment response with serum LDH levels .