Role of Reference Materials for Validation of Analytical Data in Trace Element Analysis of Biological Materials

Abstract

Analytical quality assurance is essential to obtain meaningful results in trace element analysis of biological materials. The incorporation of appropriate reference materials in the scheme of analysis is the most convenient, cost-effective mechanism by which to assess and maintain analytical data quality. The National Institute for Environmental Studies (NIES) has issued a variety of biological and environmental reference materials to serve the needs of scientists engaged in trace element analysis of these types of samples. In this paper the preparation and trace element analysis of NIES “human” reference materials - Freeze-dried Human Serum and Human Hair — and NIES food reference material - Rice Flour-Unpolished - are described.