Abstract

Introduction or background: Although rapid on-site cytological evaluation (ROSE) is widely used during transbronchial lung biopsy, its role remains unclear in electromagnetic navigation bronchoscopy (ENB)-guided peripheral lung biopsy Aims and objectives: The purpose of the present study was to evaluate the efficacy of ROSE during ENB- guided peripheral lung biopsy in the diagnosis of lung cancer. Methods: 28 patients highly suspected of having peripheral lung cancer were enrolled in this study and randomized to undergo ENB with or without ROSE. Results: Out of 28, 14 in the ROSE group, 14 in the non-ROSE group were analyzed. The sensitivity for diagnosing lung cancer was 82% in the ROSE group and 74% in the non-ROSE group, respectively. Mean biopsy number was significantly more in the ROSE group (3.5 vs. 2.8 non-ROSE, No complications were associated with the procedures. Conclusions: ROSE during ENB-guided lung biopsy is associated with a significantly higher lung cancer diagnosing yield without more complications.

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